| Long name: |
ALEXA FLUOR 350 Conjugated, GM2A Polyclonal Antibody |
| Also known as: |
Anti-GM2A PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GM2A |
| Specificity: |
This is a highly specific antibody against GM2A |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
160-193/193 |
| Subcellular location: |
Lysosome |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GM2A/SAP3 |
| Gene ID Number: |
2760 |
| Swiss Prot: |
P17900 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binds gangliosides and stimulates ganglioside GM2 degradation, GM2A also exhibits some calcium-independent phospholipase activity (By similarity), It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3, It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A, The large binding pocket can accommodate several single chain phospholipids and fatty acids |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
SAP-3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
GM2A |
| Short name: |
GM2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, GM2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4367 |
| Gene: |
GM2A |
More about : GM2A |
| Long gene name: |
GM2 ganglioside activator |
| Synonyms gene name: |
GM2 ganglioside activator protein |
| Synonyms name: |
cerebroside sulfate activator protein sphingolipid activator protein 3 |
| Locus: |
5q33, 1 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
2760 |
| Pubmed identfication: |
115863 1915857 |
| RefSeq identity: |
NM_000405 |
| Havana BLAST/BLAT: |
OTTHUMG00000130124 |
| Locus Specific Databases: |
GM2A Locus Database |