| Long name: |
Cy5, 5 Conjugated, GLDC Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GLDC |
| Specificity: |
This is a highly specific antibody against GLDC |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GLDC |
| Gene ID number: |
2731 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DLD (known as Protein L) and GLDC (known as Protein P), GCSH (known as Protein H), GCSP (glycine cleavage system P protein) or HYGN1, GLDC (glycine dehydrogenase ), GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T, GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor, Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), all of which work together to catalyze the cleavage and degradation of glycine, also known as GCE, also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms, is a 1, 020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family, The glycine cleavage system is comprised of AMT (known as Protein T) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
GCSP NKH |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
GLDC Conjugated |
| Short name: |
Conjugated, GLDC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, GLDC (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4313 |
| Gene: |
GLDC |
More about : GLDC |
| Long gene name: |
glycine decarboxylase |
| Synonyms gene name: |
glycine cleavage system protein P) glycine dehydrogenase (decarboxylating) , glycine decarboxylase, glycine dehydrogenase (decarboxylating |
| Synonyms name: |
glycine cleavage system protein P glycine dehydrogenase |
| Locus: |
9p24, 1 |
| Discovery year: |
1992-04-08 |
| GenBank acession: |
D90239 |
| Entrez gene record: |
2731 |
| Pubmed identfication: |
1993704 1996985 |
| RefSeq identity: |
NM_000170 |
| Havana BLAST/BLAT: |
OTTHUMG00000019524 |
| Locus Specific Databases: |
LRG_643 |