| Long name: |
ALEXA FLUOR 350 Conjugated, GLDC Polyclonal Antibody |
| Also known as: |
Anti-GLDC PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GLDC |
| Specificity: |
This is a highly specific antibody against GLDC |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GLDC |
| Gene ID Number: |
2731 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
DLD (known as Protein L) and GLDC (known as Protein P), GCSH (known as Protein H), GCSP (glycine cleavage system P protein) or HYGN1, GLDC (glycine dehydrogenase ), GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T, GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor, Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), all of which work together to catalyze the cleavage and degradation of glycine, also known as GCE, also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms, is a 1, 020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family, The glycine cleavage system is comprised of AMT (known as Protein T) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
GCSP NKH |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
GLDC |
| Short name: |
GLDC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, GLDC (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4313 |
| Gene: |
GLDC |
More about : GLDC |
| Long gene name: |
glycine decarboxylase |
| Synonyms gene name: |
glycine cleavage system protein P) glycine dehydrogenase (decarboxylating) , glycine decarboxylase, glycine dehydrogenase (decarboxylating |
| Synonyms name: |
glycine cleavage system protein P glycine dehydrogenase |
| Locus: |
9p24, 1 |
| Discovery year: |
1992-04-08 |
| GenBank acession: |
D90239 |
| Entrez gene record: |
2731 |
| Pubmed identfication: |
1993704 1996985 |
| RefSeq identity: |
NM_000170 |
| Havana BLAST/BLAT: |
OTTHUMG00000019524 |
| Locus Specific Databases: |
LRG_643 |