| Long name: |
Cy3 Conjugated, GGA1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GGA1 |
| Specificity: |
This is a highly specific antibody against GGA1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GGA1 |
| Gene ID number: |
26088 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ARF (ADP-ribosylation factor), ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, GGA1, GGA1 and GGA2 do not associate with each other, GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, Members of the GGA family, The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3), The cytosolic domain of memapsin 2, The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1), a connecting hinge segment, and STAM) domain followed by a GAT (GGA and TOM1) domain, and a C-terminal GAE (?adaptin ear) domain (5), and clathrin (1?), are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1, binds the VHS domains of GGA1 and GGA2 (6), but not that of memapsin 1, but they do colocalize on perinuclear membranes (2), 2, 4), GGA2 (also known as VEAR) and GGA3, The GGA family of proteins (Golgi-localized |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Properties: |
1 of the GGA1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GGA1 Conjugated |
| Short name: |
Conjugated, GGA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, GGA1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17842 |
| Gene: |
GGA1 |
More about : GGA1 |
| Long gene name: |
ARF binding protein 1 , gamma adaptin ear containing, golgi associated |
| Locus: |
22q13, 1 |
| Discovery year: |
2001-12-19 |
| GenBank acession: |
AF190862 |
| Entrez gene record: |
26088 |
| Pubmed identfication: |
10747088 10747089 16407204 |
| RefSeq identity: |
NM_013365 |
| Classification: |
ARF binding proteins , Golgi associated, gamma adaptin ear containing |
| Havana BLAST/BLAT: |
OTTHUMG00000030985 |