| Long name: |
ALEXA FLUOR 647 Conjugated, GGA1 Polyclonal Antibody |
| Also known as: |
Anti-GGA1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GGA1 |
| Specificity: |
This is a highly specific antibody against GGA1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GGA1 |
| Gene ID Number: |
26088 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ARF (ADP-ribosylation factor), ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, GGA1, GGA1 and GGA2 do not associate with each other, GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, Members of the GGA family, The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3), The cytosolic domain of memapsin 2, The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1), a connecting hinge segment, and STAM) domain followed by a GAT (GGA and TOM1) domain, and a C-terminal GAE (?adaptin ear) domain (5), and clathrin (1?), are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1, binds the VHS domains of GGA1 and GGA2 (6), but not that of memapsin 1, but they do colocalize on perinuclear membranes (2), 2, 4), GGA2 (also known as VEAR) and GGA3, The GGA family of proteins (Golgi-localized |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GGA1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
GGA1 |
| Short name: |
GGA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, GGA1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17842 |
| Gene: |
GGA1 |
More about : GGA1 |
| Long gene name: |
ARF binding protein 1 , gamma adaptin ear containing, golgi associated |
| Locus: |
22q13, 1 |
| Discovery year: |
2001-12-19 |
| GenBank acession: |
AF190862 |
| Entrez gene record: |
26088 |
| Pubmed identfication: |
10747088 10747089 16407204 |
| RefSeq identity: |
NM_013365 |
| Classification: |
ARF binding proteins , Golgi associated, gamma adaptin ear containing |
| Havana BLAST/BLAT: |
OTTHUMG00000030985 |