| Catalog number: | bs-13322R-Cy5.5 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | GCS1 Antibody, Cy5.5 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy5, 5 Conjugated, GCS1 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy5, 5, 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | GCS1 |
| Specificity: | This is a highly specific antibody against GCS1 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human GCS1 |
| Gene ID number: | 7841 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Glucosidase I catalyzes the first step in the N-linked oligosaccharide processing pathway, Glucosidase I contains a short cytosolic tail, It specifically removes the distal alpha 1, Mutations in the gene encoding Glucosidase I result in the congenital disorder glycosylation (CDG-IIb), Two point mutations in the Glucosidase I gene have been identified and result in amino acid substitutions, a single pass transmembrane domain and a large C-terminal catalytic domain located on the luminal side of the ER, dysmorphic features, feeding problems, hepatomegaly, hypoventilation, namely Arg486Thr and Phe652Leu, seizures and death, that affect polypeptide folding and active site formation, which is characterized by generalized hypotonia, 2-linked glucose residue from the Glc3-Man9-GlcNAc2 oligosaccharide precursor, Glycosylation of asparagine residues in Asn-X-Ser/Thr motifs in proteins commonly occur in the lumen of the endoplasmic reticulum (ER) |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 675nm/694nm |
| Synonyms: | GCS1 CWH41 DER7 |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: | GCS1 Conjugated |
| Short name: | Conjugated, GCS1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | 5, Cy5 |
| Alternative name: | cyanine 5, 5 coupled, GCS1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 24862 |
| Gene: | MOGS | More about : MOGS |
| Long gene name: | mannosyl-oligosaccharide glucosidase |
| Synonyms name: | glucosidase I processing A-glucosidase I |
| Locus: | 2p13, 1 |
| Discovery year: | 2009-03-24 |
| GenBank acession: | X87237 |
| Entrez gene record: | 7841 |
| Pubmed identfication: | 7635146 8786151 |
| RefSeq identity: | NM_006302 |
| Havana BLAST/BLAT: | OTTHUMG00000152886 |
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