| Long name: |
Cy3 Conjugated, FZD3/Frizzled 3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FZD3/Frizzled 3 |
| Specificity: |
This is a highly specific antibody against FZD3/Frizzled 3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
150-200/666 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human FZD3/Frizzled 3 |
| Gene ID number: |
7976 |
| Swiss Prot: |
Q9NPG1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Properties: |
1 of the FZD3/Frizzled 3 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FZD3/Frizzled 3 Conjugated |
| Short name: |
Conjugated, FZD3/Frizzled 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, FZD3/Frizzled 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4041 |
| Gene: |
FZD3 |
More about : FZD3 |
| Long gene name: |
frizzled class receptor 3 |
| Synonyms gene name: |
frizzled (Drosophila) homolog 3 frizzled homolog 3 (Drosophila) frizzled 3, seven transmembrane spanning receptor frizzled family receptor 3 |
| Locus: |
8p21, 1 |
| Discovery year: |
1998-09-17 |
| GenBank acession: |
AJ272427 |
| Entrez gene record: |
7976 |
| Pubmed identfication: |
10777673 10873558 |
| RefSeq identity: |
NM_145866 |
| Classification: |
Class F frizzled , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000102145 |