FZD3/Frizzled 3 Antibody

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Catalog number: bs-13239R
Price: 50 €
Supplier: abbex
Product name: FZD3/Frizzled 3 Antibody
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Long name: FZD3/Frizzled 3 Primary Polyclonal Antibody
Also known as: FZD3/Frizzled 3 PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: FZD3/Frizzled 3
Specificity: This is a highly specific antibody against FZD3/Frizzled 3
Modification(s): None
Modification site(s): Unmodified antibody
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 150-200/666
Subcellular location: Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FZD3/Frizzled 3
Gene ID number: 7976
Swiss Prot: Q9NPG1
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: FZD3, Frizzled-3, hFz3, Fz-3
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: FZD3/Frizzled 3
Short name: FZD3/Frizzled 3 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: FZD3/Frizzled 3 (Antibody to)
Alternative technique: antibodies
Identity: 4041
Gene: FZD3 | More about : FZD3
Long gene name: frizzled class receptor 3
Synonyms gene name: frizzled (Drosophila) homolog 3 frizzled homolog 3 (Drosophila) frizzled 3, seven transmembrane spanning receptor frizzled family receptor 3
Locus: 8p21, 1
Discovery year: 1998-09-17
GenBank acession: AJ272427
Entrez gene record: 7976
Pubmed identfication: 10777673 10873558
RefSeq identity: NM_145866
Classification: Class F frizzled , G protein-coupled receptors
Havana BLAST/BLAT: OTTHUMG00000102145

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