| Long name: |
FITC Conjugated, FYB/ADAP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FYB/ADAP |
| Specificity: |
This is a highly specific antibody against FYB/ADAP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human FYB/ADAP |
| Gene ID number: |
2533 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
RKxxYxxY) (4, SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells (1â, SKAP55 associates with SLAP-130, SKAP55 contains an amino-terminal pleckstrin homology domain and a carboxy-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i, SKAP55-R, The human Fyb gene maps to chromosome 5p13, another component of the Fyn complex, contains a coiled-coil N-terminal domain (1, similar in overall structure to SKAP55, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation (6), &euro, &euro, &ldquo, &ldquo, 1 and encodes a 783 amino acid protein (7), 2), 3), 3), 5), Fyb (Fyn binding protein) and the anchoring proteins SKAP55 (src kinase-associated phosphoprotein) and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn (1â, e |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
SLAP-130 FYB-120/130 ADAP |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FYB/ADAP Conjugated |
| Short name: |
FITC Conjugated, FYB/ADAP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
FGR, YES binding protein/ADAP (Antibody to), fluorecein coupled, FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADAP and PRO0823 and SLAP-130, FYB and IDBG-17782 and ENSG00000082074 and 2533, FYB and IDBG-629944 and ENSBTAG00000001492 and 535347, Fyb and IDBG-128115 and ENSMUSG00000022148 and 23880, nuclei, protein complex binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006607 and NLS-bearing protein import into nucleus and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0008150 and biological process and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0050852 and T cell receptor signaling pathway and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding, this GO :0005515 : protein binding, this GO :0032403 : protein complex binding, FYN binding protein |
| Identity: |
4036 |
| Gene: |
FYB |
More about : FYB |
| Long gene name: |
FYN binding protein |
| Synonyms gene name: |
FYN-binding protein (FYB-120/130) |
| Synonyms name: |
adhesion and degranulation promoting adaptor protein |
| Locus: |
5p13, 1 |
| Discovery year: |
1998-04-22 |
| GenBank acession: |
U93049 |
| Entrez gene record: |
2533 |
| Pubmed identfication: |
9115214 9207119 |
| RefSeq identity: |
NM_001465 |
| Havana BLAST/BLAT: |
OTTHUMG00000162071 |