| Long name: |
ALEXA FLUOR 647 Conjugated, FYB/ADAP Polyclonal Antibody |
| Also known as: |
Anti-FYB/ADAP PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FYB/ADAP |
| Specificity: |
This is a highly specific antibody against FYB/ADAP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FYB/ADAP |
| Gene ID Number: |
2533 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
RKxxYxxY) (4, SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells (1â, SKAP55 associates with SLAP-130, SKAP55 contains an amino-terminal pleckstrin homology domain and a carboxy-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i, SKAP55-R, The human Fyb gene maps to chromosome 5p13, another component of the Fyn complex, contains a coiled-coil N-terminal domain (1, similar in overall structure to SKAP55, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation (6), &euro, &euro, &ldquo, &ldquo, 1 and encodes a 783 amino acid protein (7), 2), 3), 3), 5), Fyb (Fyn binding protein) and the anchoring proteins SKAP55 (src kinase-associated phosphoprotein) and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn (1â, e |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
SLAP-130 FYB-120/130 ADAP |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the FYB/ADAP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
FYB/ADAP |
| Short name: |
FYB/ADAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, FGR, YES binding protein/ADAP (Antibody to), FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADAP and PRO0823 and SLAP-130, FYB and IDBG-17782 and ENSG00000082074 and 2533, FYB and IDBG-629944 and ENSBTAG00000001492 and 535347, Fyb and IDBG-128115 and ENSMUSG00000022148 and 23880, nuclei, protein complex binding, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006607 and NLS-bearing protein import into nucleus and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0008150 and biological process and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0050852 and T cell receptor signaling pathway and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding, this GO :0005515 : protein binding, this GO :0032403 : protein complex binding, FYN binding protein |
| Identity: |
4036 |
| Gene: |
FYB |
More about : FYB |
| Long gene name: |
FYN binding protein |
| Synonyms gene name: |
FYN-binding protein (FYB-120/130) |
| Synonyms name: |
adhesion and degranulation promoting adaptor protein |
| Locus: |
5p13, 1 |
| Discovery year: |
1998-04-22 |
| GenBank acession: |
U93049 |
| Entrez gene record: |
2533 |
| Pubmed identfication: |
9115214 9207119 |
| RefSeq identity: |
NM_001465 |
| Havana BLAST/BLAT: |
OTTHUMG00000162071 |