| Long name: |
ALEXA FLUOR 647 Conjugated, Fukutin Polyclonal Antibody |
| Also known as: |
Anti-Fukutin PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Fukutin |
| Specificity: |
This is a highly specific antibody against Fukutin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fukutin |
| Gene ID Number: |
282969 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
FCMD is the first human disease known to be caused by an ancient retrotransposal integration, Fukutin colocalizes with a Golgi marker and a granular cytoplasmic distribution, Fukutin deficiency affects the modification of glycosylation of DAG1 (Î, Fukutin may be located in the extracellular matrix, The fukutin gene is expressed at similar levels in control fetal and adult brain, The gene which encodes fukutin maps to human chromosome 9q31, a secreted protein, alternatively, as a secreted protein, but is much reduced in Fukuyama congenital muscular dystrophy (FCMD) brains, fukutin may cause muscular dystrophy by an unknown mechanism, is expressed in various tissues in normal individuals, suggesting that fukutin passes through the Golgi before being packaged into secretory vesicles, where it interacts with and reinforces a large complex encompassing the outside and inside of muscle membranes, which then cannot localize or function properly and may be degraded or eluted from the extracellular surface membrane of the muscle fiber, ±, -dystroglycan), Fukutin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
LGMD2I MDC1C |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Fukutin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Fukutin |
| Short name: |
Fukutin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Fukutin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17997 |
| Gene: |
FKRP |
More about : FKRP |
| Long gene name: |
fukutin related protein |
| Locus: |
19q13, 32 |
| Discovery year: |
2003-12-04 |
| GenBank acession: |
AJ314847 |
| Entrez gene record: |
79147 |
| Pubmed identfication: |
11592034 11741828 |
| RefSeq identity: |
NM_024301 |
| Havana BLAST/BLAT: |
OTTHUMG00000183177 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_761 |