| Catalog number: | bs-13226R |
|---|---|
| Price: | 729 € |
| Supplier: | genways |
| Product name: | Fukutin Antibody |
| Quantity: | 1 tube |
| Related search: |
| Long name: | Fukutin Primary Polyclonal Antibody |
|---|---|
| Also known as: | Fukutin PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | Fukutin |
| Specificity: | This is a highly specific antibody against Fukutin |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fukutin |
| Gene ID number: | 282969 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | FCMD is the first human disease known to be caused by an ancient retrotransposal integration, Fukutin colocalizes with a Golgi marker and a granular cytoplasmic distribution, Fukutin deficiency affects the modification of glycosylation of DAG1 (Î, Fukutin may be located in the extracellular matrix, The fukutin gene is expressed at similar levels in control fetal and adult brain, The gene which encodes fukutin maps to human chromosome 9q31, a secreted protein, alternatively, as a secreted protein, but is much reduced in Fukuyama congenital muscular dystrophy (FCMD) brains, fukutin may cause muscular dystrophy by an unknown mechanism, is expressed in various tissues in normal individuals, suggesting that fukutin passes through the Golgi before being packaged into secretory vesicles, where it interacts with and reinforces a large complex encompassing the outside and inside of muscle membranes, which then cannot localize or function properly and may be degraded or eluted from the extracellular surface membrane of the muscle fiber, ±, -dystroglycan), Fukutin |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | Chromosome 10 open reading frame 125, FUCM_HUMAN, FUCU, Fucose mutarotase, Protein fucU homolog, C10orf125 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | Fukutin |
| Short name: | Fukutin Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | Fukutin (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 17997 |
| Gene: | FKRP | More about : FKRP |
| Long gene name: | fukutin related protein |
| Synonyms: | LGMD2I MDC1C |
| Locus: | 19q13, 32 |
| Discovery year: | 2003-12-04 |
| GenBank acession: | AJ314847 |
| Entrez gene record: | 79147 |
| Pubmed identfication: | 11592034 11741828 |
| RefSeq identity: | NM_024301 |
| Havana BLAST/BLAT: | OTTHUMG00000183177 |
| Locus Specific Databases: | Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_761 |
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