| Catalog number: | bs-13188R-Biotin |
|---|---|
| Price: | 673 € |
| Supplier: | abbex |
| Product name: | FMRP (Ser500) Antibody, Biotin Conjugated |
| Quantity: | 25 mg |
| Related search: |
| Long name: | Biotin Conjugated, FMRP (Ser500) Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | FMRP Ser500 |
| Specificity: | This is a highly specific antibody against FMRP Ser500 |
| Modification: | Phosphorylation |
| Modification site: | Ser500 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 480-530/632 |
| Subcellular location: | Nucleus, Cytoplasm |
| Source: | KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500 |
| Gene ID number: | 2332 |
| Swiss Prot: | Q06787 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Associated with polysomes, Binds strongly to poly(G), Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression, In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity), May play a role in the transport of mRNA from the nucleus to the cytoplasm, RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs, binds moderately to poly(U) but shows very little binding to poly(A) or poly(C), Translation repressor |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | FMRP FRAXA MGC87458 |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | FMRP (Ser500) Conjugated |
| Short name: | Conjugated, FMRP (Ser500) Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, FMRP (Ser500) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 3775 |
| Gene: | FMR1 | More about : FMR1 |
| Long gene name: | fragile X mental retardation 1 |
| Synonyms gene: | POF1 POF |
| Synonyms gene name: | premature ovarian failure 1 |
| Locus: | Xq27, 3 |
| Discovery year: | 1992-01-17 |
| GenBank acession: | X69962 |
| Entrez gene record: | 2332 |
| Pubmed identfication: | 1572655 |
| RefSeq identity: | NM_002024 |
| Havana BLAST/BLAT: | OTTHUMG00000022606 |
| Locus Specific Databases: | Mental Retardation database LRG_762 |
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