| Long name: |
FMRP (Ser500) Primary Polyclonal Antibody |
| Also known as: |
FMRP (Ser500) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FMRP Ser500 |
| Specificity: |
This is a highly specific antibody against FMRP Ser500 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser500 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
480-530/632 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500 |
| Gene ID number: |
2332 |
| Swiss Prot: |
Q06787 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Associated with polysomes, Binds strongly to poly(G), Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression, In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity), May play a role in the transport of mRNA from the nucleus to the cytoplasm, RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs, binds moderately to poly(U) but shows very little binding to poly(A) or poly(C), Translation repressor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FMR1, FMRP, FRAXA, Fragile X mental retardation protein 1, POF1, Protein FMR-1, POF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FMRP (Ser500) |
| Short name: |
FMRP (Ser500) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FMRP (Ser500) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3775 |
| Gene: |
FMR1 |
More about : FMR1 |
| Long gene name: |
fragile X mental retardation 1 |
| Synonyms gene: |
POF1 POF |
| Synonyms gene name: |
premature ovarian failure 1 |
| Synonyms: |
FMRP FRAXA MGC87458 |
| Locus: |
Xq27, 3 |
| Discovery year: |
1992-01-17 |
| GenBank acession: |
X69962 |
| Entrez gene record: |
2332 |
| Pubmed identfication: |
1572655 |
| RefSeq identity: |
NM_002024 |
| Havana BLAST/BLAT: |
OTTHUMG00000022606 |
| Locus Specific Databases: |
Mental Retardation database LRG_762 |