| Long name: |
FITC Conjugated, EYA4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EYA4 |
| Specificity: |
This is a highly specific antibody against EYA4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human EYA4 |
| Gene ID number: |
2070 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family (1), DACH, EYA is one of four members of the eyes absent family (1), EYA4 (eyes absent) (1), EYA4 is expressed in the craniofacial mesenchyme, EYA4 may cause oculo-dento-digital syndrome, Premature stop codon mutations in EYA4 cause postlingual, SIX translocates EYA1-3 to the nucleus, The conserved region in other EYA proteins interacts with SIX, This shows that EYA4 is also vital to the mature organ of Corti (2), and G-proteins, and G-proteins can stop this interaction (3, and the limb (1), based on its expression pattern and map postion (1), progressive autosomal dominant hearing loss in humans (2), the dermamyotome, which regulate transcription in early embryonic development (1, 2, 3, 4), 4), A gene of chromosome 6q23 encodes the 640 amino acid protein |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
EYA4 Conjugated |
| Short name: |
FITC Conjugated, EYA4 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, EYA4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3522 |
| Gene: |
EYA4 |
More about : EYA4 |
| Long gene name: |
EYA transcriptional coactivator and phosphatase 4 |
| Synonyms gene: |
DFNA10 CMD1J |
| Synonyms gene name: |
eyes absent (Drosophila) homolog 4 eyes absent homolog 4 (Drosophila) |
| Locus: |
6q23, 2 |
| Discovery year: |
1998-07-15 |
| GenBank acession: |
Y17114 |
| Entrez gene record: |
2070 |
| Pubmed identfication: |
9887327 11159937 |
| RefSeq identity: |
NM_004100 |
| Classification: |
EYA transcriptional coactivator and phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000015602 |
| Locus Specific Databases: |
Hereditary Hearing Loss Homepage LRG_418 |