| Long name: |
EYA4 Primary Polyclonal Antibody |
| Also known as: |
EYA4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
EYA4 |
| Specificity: |
This is a highly specific antibody against EYA4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EYA4 |
| Gene ID number: |
2070 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family (1), DACH, EYA is one of four members of the eyes absent family (1), EYA4 (eyes absent) (1), EYA4 is expressed in the craniofacial mesenchyme, EYA4 may cause oculo-dento-digital syndrome, Premature stop codon mutations in EYA4 cause postlingual, SIX translocates EYA1-3 to the nucleus, The conserved region in other EYA proteins interacts with SIX, This shows that EYA4 is also vital to the mature organ of Corti (2), and G-proteins, and G-proteins can stop this interaction (3, and the limb (1), based on its expression pattern and map postion (1), progressive autosomal dominant hearing loss in humans (2), the dermamyotome, which regulate transcription in early embryonic development (1, 2, 3, 4), 4), A gene of chromosome 6q23 encodes the 640 amino acid protein |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DFNA 10, DFNA10, Deafness, EYA 4, EYA4_HUMAN, Eyes absent 4, Eyes absent homolog 4, Eyes absent homolog 4 Drosophila, HGNC:3522, OTTHUMP00000040267, autosomal dominant 10, dJ78N10, dJ78N10, eya4, 1 eyes absent, 1 eyes absent Drosophila homolog 4, CMD1J |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
EYA4 |
| Short name: |
EYA4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
EYA4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3522 |
| Gene: |
EYA4 |
More about : EYA4 |
| Long gene name: |
EYA transcriptional coactivator and phosphatase 4 |
| Synonyms gene: |
DFNA10 CMD1J |
| Synonyms gene name: |
eyes absent (Drosophila) homolog 4 eyes absent homolog 4 (Drosophila) |
| Locus: |
6q23, 2 |
| Discovery year: |
1998-07-15 |
| GenBank acession: |
Y17114 |
| Entrez gene record: |
2070 |
| Pubmed identfication: |
9887327 11159937 |
| RefSeq identity: |
NM_004100 |
| Classification: |
EYA transcriptional coactivator and phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000015602 |
| Locus Specific Databases: |
Hereditary Hearing Loss Homepage LRG_418 |