| Long name: |
FITC Conjugated, DUSP10/MKP5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DUSP10/MKP5 |
| Specificity: |
This is a highly specific antibody against DUSP10/MKP5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DUSP10/MKP5 |
| Gene ID number: |
11221 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DSP gene expression is induced by a host of growth factors and/or cellular stresses, Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus, MKP-5 has been implicated in cell proliferation and apoptosis, MKP-5 preferentially binds to p38, SAPK/JNK and p38, but also to SAPK/JNK, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, tumor invasion and immune responses, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases, Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MKP-5 MKP5 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DUSP10/MKP5 Conjugated |
| Short name: |
FITC Conjugated, DUSP10/MKP5 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DUSP10/MKP5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3065 |
| Gene: |
DUSP10 |
More about : DUSP10 |
| Long gene name: |
dual specificity phosphatase 10 |
| Locus: |
1q41 |
| Discovery year: |
1999-11-26 |
| GenBank acession: |
AB026436 |
| Entrez gene record: |
11221 |
| Pubmed identfication: |
10391943 10597297 |
| RefSeq identity: |
NM_007207 |
| Classification: |
MAP kinase phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000037269 |