| Long name: |
DUSP10/MKP5 Primary Polyclonal Antibody |
| Also known as: |
DUSP10/MKP5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DUSP10/MKP5 |
| Specificity: |
This is a highly specific antibody against DUSP10/MKP5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DUSP10/MKP5 |
| Gene ID number: |
11221 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
DSP gene expression is induced by a host of growth factors and/or cellular stresses, Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus, MKP-5 has been implicated in cell proliferation and apoptosis, MKP-5 preferentially binds to p38, SAPK/JNK and p38, but also to SAPK/JNK, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, tumor invasion and immune responses, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases, Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DUS10_HUMAN, DUSP 10, DUSP10, DUSP10 protein, Dual specicity phosphatase MKP 5, Dual specicity phosphatase MKP5, Dual specicity protein phosphatase 10, MAP kinase phosphatase 5, MKP 5, MKP-5, MKP5, Mitogen activated protein kinase phosphatase 5, Mitogen-activated protein kinase phosphatase 5, Serine/threonine specic protein phosphatase, Dual specicity phosphatase 10 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DUSP10/MKP5 |
| Short name: |
DUSP10/MKP5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DUSP10/MKP5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3065 |
| Gene: |
DUSP10 |
More about : DUSP10 |
| Long gene name: |
dual specificity phosphatase 10 |
| Synonyms: |
MKP-5 MKP5 |
| Locus: |
1q41 |
| Discovery year: |
1999-11-26 |
| GenBank acession: |
AB026436 |
| Entrez gene record: |
11221 |
| Pubmed identfication: |
10391943 10597297 |
| RefSeq identity: |
NM_007207 |
| Classification: |
MAP kinase phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000037269 |