| Long name: |
ALEXA FLUOR 647 Conjugated, DUSP10/MKP5 Polyclonal Antibody |
| Also known as: |
Anti-DUSP10/MKP5 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DUSP10/MKP5 |
| Specificity: |
This is a highly specific antibody against DUSP10/MKP5 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DUSP10/MKP5 |
| Gene ID Number: |
11221 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
DSP gene expression is induced by a host of growth factors and/or cellular stresses, Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus, MKP-5 has been implicated in cell proliferation and apoptosis, MKP-5 preferentially binds to p38, SAPK/JNK and p38, but also to SAPK/JNK, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, tumor invasion and immune responses, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases, Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MKP-5 MKP5 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DUSP10/MKP5 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
DUSP10/MKP5 |
| Short name: |
DUSP10/MKP5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, DUSP10/MKP5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3065 |
| Gene: |
DUSP10 |
More about : DUSP10 |
| Long gene name: |
dual specificity phosphatase 10 |
| Locus: |
1q41 |
| Discovery year: |
1999-11-26 |
| GenBank acession: |
AB026436 |
| Entrez gene record: |
11221 |
| Pubmed identfication: |
10391943 10597297 |
| RefSeq identity: |
NM_007207 |
| Classification: |
MAP kinase phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000037269 |