| Long name: |
Recombinant Human Serine/threonine-protein kinase Chk2 (CHEK2) |
| Alternative names: |
CHK2 checkpoint homolog, CHK2 checkpoint homolog, Cds1 homolog, Checkpoint kinase 2, Hucds1, Serine/threonine-protein kinase Chk2, cds1 homolog, checkpoint kinase 2, checkpoint-like protein CHK2, hCds1, serine/threonine-protein kinase Chk2, serine/threonine-protein kinase Chk2 isoform c |
| Gene name: |
CHEK2 |
| Other gene names: |
CDS1, CDS1, CHEK2, CHK2, CHK2, HuCds1, Hucds1, LFS2, PP1425, RAD53, RAD53, hCds1, hCds1, CHEK2 |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Serine/threonine-protein kinase Chk2(CHEK2) is a recombinant protein expressed in Mammalian Cell |
| Product category: |
Recombinant Proteins |
| Expression system: |
Mammalian Cell |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
Serine/threonine-protein kinase Chk2 (CHEK2) |
| Short name: |
Serine/threonine-protein kinase Chk2 (CHEK2) |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Serine/threonine-protein phosphorylation catalyst Chk2 (checkpoint kinase 2), H |
| Alternative to gene target: |
CDS1 and CHK2 and hCds1 and HuCds1 and LFS2 and PP1425 and RAD53, CHEK2 and IDBG-3314 and ENSG00000183765 and 11200, CHEK2 and IDBG-636030 and ENSBTAG00000004956 and 518897, Chek2 and IDBG-190635 and ENSMUSG00000029521 and 50883, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006975 and DNA damage induced protein phosphorylation and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0016301 and kinase activity and molecular function this GO :0016605 and PML body and cellular component this GO :0016772 and transferase activity, DNA-templated and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050821 and protein stabilization and biological process this GO :0072428 and signal transduction involved in intra-S DNA damage checkpoint and biological process this GO :0090307 and spindle assembly involved in mitosis and biological process this GO :0090399 and replicative senescence and biological process, nuclei, telomeric region and cellular component this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0006302 and double-strand break repair and biological process this GO :0006351 and transcription, this GO :0000077 and DNA damage checkpoint and biological process this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000781 and chromosome, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046872 : metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901 : protein kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046872 : metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0042176 and regulation of protein catabolic process and biological process this GO :0042770 and signal transduction in response to DNA damage and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0044257 and cellular protein catabolic process and biological process this GO :0045893 and positive regulation of transcription, checkpoint kinase 2 |
| Identity: |
16627 |
| Gene: |
CHEK2 |
More about : CHEK2 |
| Long gene name: |
checkpoint kinase 2 |
| Synonyms gene: |
RAD53 |
| Synonyms gene name: |
CHK2 (checkpoint, S, pombe) , pombe) homolog CHK2 checkpoint homolog (S |
| Synonyms: |
CDS1 CHK2 HuCds1 PP1425 bA444G7 |
| Locus: |
22q12, 1 |
| Discovery year: |
2001-09-19 |
| GenBank acession: |
AF086904 |
| Entrez gene record: |
11200 |
| Pubmed identfication: |
9836640 10097108 |
| RefSeq identity: |
NM_001005735 |
| Havana BLAST/BLAT: |
OTTHUMG00000151023 |
| Locus Specific Databases: |
LRG_302 |