| Also known as: |
CHEK2 / CHK2 |
| Other names: |
CHK2 checkpoint homolog, CHK2 checkpoint homolog, Cds1 homolog, Checkpoint kinase 2, Hucds1, Serine/threonine-protein kinase Chk2, cds1 homolog, checkpoint kinase 2, checkpoint-like protein CHK2, hCds1, serine/threonine-protein kinase Chk2, serine/threonine-protein kinase Chk2 isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CHEK2 |
| Gene name synonims: |
CHK2 |
| Other gene names: |
CDS1, CDS1, CHEK2, CHK2, CHK2, HuCds1, Hucds1, LFS2, PP1425, RAD53, RAD53, hCds1, hCds1, CHEK2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
1, 1, 73C175 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, A synthetic peptide obtained from human Chk2 protein sequence was used as immunogen |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 02% sodium azide, PBS |
| Storage and shipping: |
Cycles of freeze/thaw can damage the antibodies and recude their activity, For shorter storage the antibody can be kept at +4 degrees Celsius, therefore should be avoided as much as possible, For long term storage keep the antibody at -70C or -80 |
| Tested applications:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
1, 1] (IgG1) CHEK2 / CHK2, Monoclonal [ 73C175 |
| Short name: |
1, 1] (IgG1) CHEK2 / CHK2 Antibody, Mouse Monoclonal [clone 73C175 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens checkpoint kinase 2 / CHK2 (Antibody to), 1, 1] (IgG1) to H, Mouse monoclonal [clonality 73C175 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CDS1 and CHK2 and hCds1 and HuCds1 and LFS2 and PP1425 and RAD53, CHEK2 and IDBG-3314 and ENSG00000183765 and 11200, CHEK2 and IDBG-636030 and ENSBTAG00000004956 and 518897, Chek2 and IDBG-190635 and ENSMUSG00000029521 and 50883, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006975 and DNA damage induced protein phosphorylation and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0016301 and kinase activity and molecular function this GO :0016605 and PML body and cellular component this GO :0016772 and transferase activity, DNA-templated and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050821 and protein stabilization and biological process this GO :0072428 and signal transduction involved in intra-S DNA damage checkpoint and biological process this GO :0090307 and spindle assembly involved in mitosis and biological process this GO :0090399 and replicative senescence and biological process, nuclei, telomeric region and cellular component this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0006302 and double-strand break repair and biological process this GO :0006351 and transcription, this GO :0000077 and DNA damage checkpoint and biological process this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000781 and chromosome, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046872 : metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901 : protein kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046872 : metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0042176 and regulation of protein catabolic process and biological process this GO :0042770 and signal transduction in response to DNA damage and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0044257 and cellular protein catabolic process and biological process this GO :0045893 and positive regulation of transcription, checkpoint kinase 2 |
| Identity: |
16627 |
| Gene: |
CHEK2 |
More about : CHEK2 |
| Long gene name: |
checkpoint kinase 2 |
| Synonyms gene: |
RAD53 |
| Synonyms gene name: |
CHK2 (checkpoint, S, pombe) , pombe) homolog CHK2 checkpoint homolog (S |
| Synonyms: |
CDS1 CHK2 HuCds1 PP1425 bA444G7 |
| Locus: |
22q12, 1 |
| Discovery year: |
2001-09-19 |
| GenBank acession: |
AF086904 |
| Entrez gene record: |
11200 |
| Pubmed identfication: |
9836640 10097108 |
| RefSeq identity: |
NM_001005735 |
| Havana BLAST/BLAT: |
OTTHUMG00000151023 |
| Locus Specific Databases: |
LRG_302 |