| Long name: |
FITC Conjugated, ASPP2/p53BP2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ASPP2/p53BP2 |
| Specificity: |
This is a highly specific antibody against ASPP2/p53BP2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1090-1128/1128 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human ASPP2 |
| Gene ID number: |
7159 |
| Swiss Prot: |
Q13625 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Impedes cell cycle progression at G2/M, Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, Its apoptosis-stimulating activity is inhibited by its interaction with DDX42, Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo, and thereby decreases APPBP1 ability to induce apoptosis, Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PPP1R13A ASPP2 53BP2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ASPP2/p53BP2 Conjugated |
| Short name: |
FITC Conjugated, ASPP2/p53BP2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, ASPP2/p53BP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12000 |
| Gene: |
TP53BP2 |
More about : TP53BP2 |
| Long gene name: |
tumor protein p53 binding protein 2 |
| Synonyms gene name: |
2 , tumor protein p53-binding protein |
| Locus: |
1q41 |
| Discovery year: |
1997-06-24 |
| GenBank acession: |
U09582 |
| Entrez gene record: |
7159 |
| Pubmed identfication: |
8668206 8016121 |
| RefSeq identity: |
NM_001031685 NM_005426 |
| Classification: |
Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000037379 |