| Long name: |
ALEXA FLUOR 647 Conjugated, ASPP2/p53BP2 Polyclonal Antibody |
| Also known as: |
Anti-ASPP2/p53BP2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ASPP2/p53BP2 |
| Specificity: |
This is a highly specific antibody against ASPP2/p53BP2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1090-1128/1128 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASPP2 |
| Gene ID Number: |
7159 |
| Swiss Prot: |
Q13625 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Impedes cell cycle progression at G2/M, Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, Its apoptosis-stimulating activity is inhibited by its interaction with DDX42, Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo, and thereby decreases APPBP1 ability to induce apoptosis, Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PPP1R13A ASPP2 53BP2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ASPP2/p53BP2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ASPP2/p53BP2 |
| Short name: |
ASPP2/p53BP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, ASPP2/p53BP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12000 |
| Gene: |
TP53BP2 |
More about : TP53BP2 |
| Long gene name: |
tumor protein p53 binding protein 2 |
| Synonyms gene name: |
2 , tumor protein p53-binding protein |
| Locus: |
1q41 |
| Discovery year: |
1997-06-24 |
| GenBank acession: |
U09582 |
| Entrez gene record: |
7159 |
| Pubmed identfication: |
8668206 8016121 |
| RefSeq identity: |
NM_001031685 NM_005426 |
| Classification: |
Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000037379 |