| Long name: |
ASPP2/p53BP2 Primary Polyclonal Antibody |
| Also known as: |
ASPP2/p53BP2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ASPP2/p53BP2 |
| Specificity: |
This is a highly specific antibody against ASPP2/p53BP2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1090-1128/1128 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASPP2 |
| Gene ID number: |
7159 |
| Swiss Prot: |
Q13625 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Impedes cell cycle progression at G2/M, Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, Its apoptosis-stimulating activity is inhibited by its interaction with DDX42, Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo, and thereby decreases APPBP1 ability to induce apoptosis, Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
53BP2, ASPP2, Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, P53BP2, PPP1R13A, Renal carcinoma antigen NY-REN-51, TP53BP2, Tumor suppressor p53-binding protein 2, p53-binding protein 2, BBP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ASPP2/p53BP2 |
| Short name: |
ASPP2/p53BP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ASPP2/p53BP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12000 |
| Gene: |
TP53BP2 |
More about : TP53BP2 |
| Long gene name: |
tumor protein p53 binding protein 2 |
| Synonyms gene name: |
2 , tumor protein p53-binding protein |
| Synonyms: |
PPP1R13A ASPP2 53BP2 |
| Locus: |
1q41 |
| Discovery year: |
1997-06-24 |
| GenBank acession: |
U09582 |
| Entrez gene record: |
7159 |
| Pubmed identfication: |
8668206 8016121 |
| RefSeq identity: |
NM_001031685 NM_005426 |
| Classification: |
Ankyrin repeat domain containing Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000037379 |