| Long name: |
ATIC/AICAR transformylase Antibody |
| Also known as: |
ATIC/AICAR transformylase Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ATIC/AICAR transformylase |
| Specificity: |
This is a highly specific antibody against ATIC/AICAR transformylase |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATIC/AICAR transformylase |
| Gene ID number: |
471 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, Defects in the ATIC transformylase gene can cause AICA-rebsuria, Individuals with AICA-rebosuria accumulate AICA-riboside, Mental retardation, Patients also excrete very large amounts of AICA-riboside in the urine, also designated AICA-ribosiduria, also designated ZMP, an inborn error in purine biosynthesis that is neurologically cataclysmic, and its derivatives in erythrocytes and fibroblasts, dysmorphic features and congenital blindness are all symptoms of this disease, epilepsy, playing an important role in the production of nucleotides and IMP, The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase, 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, AICAR, AICAR formyltransferase/IMP cyclohydrolase bunctional enzyme, AICAR transformylase, AICARFT, AICARFT/IMPCHASE, ATIC, Bunctional purine biosynthesis protein PURH, FLJ93545, IMP cyclohydrolase, IMP synthase, IMP synthetase, IMPCHASE, Inosinicase, OK/SW-cl, PUR9_HUMAN, PURH, Phosphoribosylaminoimidazolecarboxamide formyltransferase, Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase, 5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase, 86 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ATIC/AICAR transformylase |
| Short name: |
ATIC/AICAR transformylase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ATIC/AICAR transformylase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
794 |
| Gene: |
ATIC |
More about : ATIC |
| Long gene name: |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| Synonyms: |
PURH AICARFT IMPCHASE |
| Synonyms name: |
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase |
| Locus: |
2q35 |
| Discovery year: |
1997-05-15 |
| Entrez gene record: |
471 |
| Pubmed identfication: |
8567683 9378707 |
| RefSeq identity: |
NM_004044 |
| Havana BLAST/BLAT: |
OTTHUMG00000133023 |