| Long name: |
Cy7 Conjugated, ATIC/AICAR transformylase Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ATIC/AICAR transformylase |
| Specificity: |
This is a highly specific antibody against ATIC/AICAR transformylase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ATIC/AICAR transformylase |
| Gene ID number: |
471 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, Defects in the ATIC transformylase gene can cause AICA-rebsuria, Individuals with AICA-rebosuria accumulate AICA-riboside, Mental retardation, Patients also excrete very large amounts of AICA-riboside in the urine, also designated AICA-ribosiduria, also designated ZMP, an inborn error in purine biosynthesis that is neurologically cataclysmic, and its derivatives in erythrocytes and fibroblasts, dysmorphic features and congenital blindness are all symptoms of this disease, epilepsy, playing an important role in the production of nucleotides and IMP, The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
PURH AICARFT IMPCHASE |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
ATIC/AICAR transformylase Conjugated |
| Short name: |
Conjugated, ATIC/AICAR transformylase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, ATIC/AICAR transformylase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
794 |
| Gene: |
ATIC |
More about : ATIC |
| Long gene name: |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| Synonyms name: |
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase |
| Locus: |
2q35 |
| Discovery year: |
1997-05-15 |
| Entrez gene record: |
471 |
| Pubmed identfication: |
8567683 9378707 |
| RefSeq identity: |
NM_004044 |
| Havana BLAST/BLAT: |
OTTHUMG00000133023 |