| Long name: |
ALEXA FLUOR 350 Conjugated, ATIC/AICAR transformylase Antibody |
| Also known as: |
Anti-ATIC/AICAR transformylase PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ATIC/AICAR transformylase |
| Specificity: |
This is a highly specific antibody against ATIC/AICAR transformylase |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATIC/AICAR transformylase |
| Gene ID Number: |
471 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, Defects in the ATIC transformylase gene can cause AICA-rebsuria, Individuals with AICA-rebosuria accumulate AICA-riboside, Mental retardation, Patients also excrete very large amounts of AICA-riboside in the urine, also designated AICA-ribosiduria, also designated ZMP, an inborn error in purine biosynthesis that is neurologically cataclysmic, and its derivatives in erythrocytes and fibroblasts, dysmorphic features and congenital blindness are all symptoms of this disease, epilepsy, playing an important role in the production of nucleotides and IMP, The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
PURH AICARFT IMPCHASE |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
ATIC/AICAR transformylase |
| Short name: |
ATIC/AICAR transformylase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, ATIC/AICAR transformylase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
794 |
| Gene: |
ATIC |
More about : ATIC |
| Long gene name: |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| Synonyms name: |
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase |
| Locus: |
2q35 |
| Discovery year: |
1997-05-15 |
| Entrez gene record: |
471 |
| Pubmed identfication: |
8567683 9378707 |
| RefSeq identity: |
NM_004044 |
| Havana BLAST/BLAT: |
OTTHUMG00000133023 |