| Long name: |
Cy3 Conjugated, ARID1B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ARID1B |
| Specificity: |
This is a highly specific antibody against ARID1B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1550-1600/2236 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human ARID1B |
| Gene ID number: |
57492 |
| Swiss Prot: |
Q8NFD5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As neural progenitors exit mitosis and differentiate into neurons, Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex), Binds DNA non-specifically, During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
KIAA1235 ELD/OSA1 p250R BAF250b DAN15 6A3-5 |
| Properties: |
1 of the ARID1B Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ARID1B Conjugated |
| Short name: |
Conjugated, ARID1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, ARID1B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18040 |
| Gene: |
ARID1B |
More about : ARID1B |
| Long gene name: |
AT-rich interaction domain 1B |
| Synonyms gene name: |
AT rich interactive domain 1B (SWI1-like) |
| Locus: |
6q25, 3 |
| Discovery year: |
2004-01-28 |
| GenBank acession: |
AF521671 |
| Entrez gene record: |
57492 |
| RefSeq identity: |
NM_020732 |
| Classification: |
AT-rich interaction domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015890 |
| Locus Specific Databases: |
LRG_861 |