| Long name: |
ALEXA FLUOR 647 Conjugated, ARID1B Polyclonal Antibody |
| Also known as: |
Anti-ARID1B PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ARID1B |
| Specificity: |
This is a highly specific antibody against ARID1B |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1550-1600/2236 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARID1B |
| Gene ID Number: |
57492 |
| Swiss Prot: |
Q8NFD5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
As neural progenitors exit mitosis and differentiate into neurons, Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex), Binds DNA non-specifically, During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
KIAA1235 ELD/OSA1 p250R BAF250b DAN15 6A3-5 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ARID1B Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ARID1B |
| Short name: |
ARID1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, ARID1B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18040 |
| Gene: |
ARID1B |
More about : ARID1B |
| Long gene name: |
AT-rich interaction domain 1B |
| Synonyms gene name: |
AT rich interactive domain 1B (SWI1-like) |
| Locus: |
6q25, 3 |
| Discovery year: |
2004-01-28 |
| GenBank acession: |
AF521671 |
| Entrez gene record: |
57492 |
| RefSeq identity: |
NM_020732 |
| Classification: |
AT-rich interaction domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015890 |
| Locus Specific Databases: |
LRG_861 |