| Long name: |
ARID1B Primary Polyclonal Antibody |
| Also known as: |
ARID1B PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ARID1B |
| Specificity: |
This is a highly specific antibody against ARID1B |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1550-1600/2236 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARID1B |
| Gene ID number: |
57492 |
| Swiss Prot: |
Q8NFD5 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
As neural progenitors exit mitosis and differentiate into neurons, Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex), Binds DNA non-specifically, During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
6A3-5, ARID domain-containing protein 1B, ARID1B, AT-rich interactive domain-containing protein 1B, BAF250B, BRG1-associated factor 250b, BRG1-binding protein hELD/OSA1, BRIGHT, DAN15, ELD/OSA1, KIAA1235, MRD12, Osa homolog 2, P250R, hOsa2, OSA2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ARID1B |
| Short name: |
ARID1B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ARID1B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18040 |
| Gene: |
ARID1B |
More about : ARID1B |
| Long gene name: |
AT-rich interaction domain 1B |
| Synonyms gene name: |
AT rich interactive domain 1B (SWI1-like) |
| Synonyms: |
KIAA1235 ELD/OSA1 p250R BAF250b DAN15 6A3-5 |
| Locus: |
6q25, 3 |
| Discovery year: |
2004-01-28 |
| GenBank acession: |
AF521671 |
| Entrez gene record: |
57492 |
| RefSeq identity: |
NM_020732 |
| Classification: |
AT-rich interaction domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015890 |
| Locus Specific Databases: |
LRG_861 |