YKL39/CHI3L2 Antibody, Biotin Conjugated

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Catalog number: bs-12358R-Biotin
Price: 322 €
Supplier: ABM lentivectors
Product name: YKL39/CHI3L2 Antibody, Biotin Conjugated
Quantity: 1.0 µg DNA
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More details :

Long name: Biotin Conjugated, YKL39/CHI3L2 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Biotinylated
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: YKL39/CHI3L2
Specificity: This is a highly specific antibody against YKL39/CHI3L2
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic peptide derived from human YKL39/CHI3L2
Gene ID number: 7690
Tested applications: IHC-P, WB
Recommended dilutions: IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity: Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Additionally, Although related to bacterial chitinases, Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, YKL-39 binds glycan structures with high affinity, YKL-39 is upregulated in early degenerative cartilage diseases (such as RA) and may be a marker of chondrocyte activation in these autoimmune conditions, YKL-39 lacks the characteristic glutamate active site and, does not have enzymatic chitinase activity, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid joint disease, thus, YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms: YKL-39 YKL39
Properties: Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: YKL39/CHI3L2 Conjugated
Short name: Conjugated, YKL39/CHI3L2 Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Biotin
Alternative name: biotinilated coupled, YKL39/CHI3L2 (Antibody to)
Alternative technique: antibodies
Identity: 1933
Gene: CHI3L2 | More about : CHI3L2
Long gene name: chitinase 3 like 2
Synonyms gene name: chitinase 3-like 2
Locus: 1p13, 2
Discovery year: 1994-12-20
GenBank acession: U49835
Entrez gene record: 1117
Pubmed identfication: 8702629
RefSeq identity: NM_004000
Classification: Chitinases
Havana BLAST/BLAT: OTTHUMG00000012174

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