| Catalog number: | bs-12358R-Biotin |
|---|---|
| Price: | 322 € |
| Supplier: | ABM lentivectors |
| Product name: | YKL39/CHI3L2 Antibody, Biotin Conjugated |
| Quantity: | 1.0 µg DNA |
| Related search: |
| Long name: | Biotin Conjugated, YKL39/CHI3L2 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | YKL39/CHI3L2 |
| Specificity: | This is a highly specific antibody against YKL39/CHI3L2 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human YKL39/CHI3L2 |
| Gene ID number: | 7690 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Additionally, Although related to bacterial chitinases, Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, YKL-39 binds glycan structures with high affinity, YKL-39 is upregulated in early degenerative cartilage diseases (such as RA) and may be a marker of chondrocyte activation in these autoimmune conditions, YKL-39 lacks the characteristic glutamate active site and, does not have enzymatic chitinase activity, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid joint disease, thus, YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | YKL-39 YKL39 |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | YKL39/CHI3L2 Conjugated |
| Short name: | Conjugated, YKL39/CHI3L2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, YKL39/CHI3L2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 1933 |
| Gene: | CHI3L2 | More about : CHI3L2 |
| Long gene name: | chitinase 3 like 2 |
| Synonyms gene name: | chitinase 3-like 2 |
| Locus: | 1p13, 2 |
| Discovery year: | 1994-12-20 |
| GenBank acession: | U49835 |
| Entrez gene record: | 1117 |
| Pubmed identfication: | 8702629 |
| RefSeq identity: | NM_004000 |
| Classification: | Chitinases |
| Havana BLAST/BLAT: | OTTHUMG00000012174 |
| bs-12358R-Biotin | YKL39/CHI3L2 Antibody, Biotin Conjugated | 0.1ml | 333 € | Bioss Primary Conjugated Antibodies | human |
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