| Long name: |
ALEXA FLUOR 488 Conjugated, YKL39/CHI3L2 Polyclonal Antibody |
| Also known as: |
Anti-YKL39/CHI3L2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
YKL39/CHI3L2 |
| Specificity: |
This is a highly specific antibody against YKL39/CHI3L2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human YKL39/CHI3L2 |
| Gene ID Number: |
7690 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Additionally, Although related to bacterial chitinases, Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, YKL-39 binds glycan structures with high affinity, YKL-39 is upregulated in early degenerative cartilage diseases (such as RA) and may be a marker of chondrocyte activation in these autoimmune conditions, YKL-39 lacks the characteristic glutamate active site and, does not have enzymatic chitinase activity, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid joint disease, thus, YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
YKL-39 YKL39 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the YKL39/CHI3L2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
YKL39/CHI3L2 |
| Short name: |
YKL39/CHI3L2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, YKL39/CHI3L2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1933 |
| Gene: |
CHI3L2 |
More about : CHI3L2 |
| Long gene name: |
chitinase 3 like 2 |
| Synonyms gene name: |
chitinase 3-like 2 |
| Locus: |
1p13, 2 |
| Discovery year: |
1994-12-20 |
| GenBank acession: |
U49835 |
| Entrez gene record: |
1117 |
| Pubmed identfication: |
8702629 |
| RefSeq identity: |
NM_004000 |
| Classification: |
Chitinases |
| Havana BLAST/BLAT: |
OTTHUMG00000012174 |