| Long name: |
Biotin Conjugated, TUG/ASPC Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TUG/ASPC |
| Specificity: |
This is a highly specific antibody against TUG/ASPC |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TUG/ASPC |
| Gene ID number: |
79058 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes, Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin, Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, Insulin mobilizes this pool of retained Glut4 by releasing the tether, TUG (ASPL in humans) regulates the trafficking of glucose via Glut4, TUG acts by trapping endocytosed Glut4 and tethering it intracellularly, fat metabolism and prolonged longevity, it is necessary for sustained growth, normal cellular glucose, Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ASPS ASPL UBXD9 UBXN9 TUG |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TUG/ASPC Conjugated |
| Short name: |
Conjugated, TUG/ASPC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, TUG/ASPC (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13825 |
| Gene: |
ASPSCR1 |
More about : ASPSCR1 |
| Long gene name: |
ASPSCR1, UBX domain containing tether for SLC2A4 |
| Synonyms gene name: |
alveolar soft part sarcoma chromosome region, candidate 1 |
| Synonyms name: |
UBX domain protein 9 Tether containing UBX domain for GLUT4 |
| Locus: |
17q25, 3 |
| Discovery year: |
2001-04-05 |
| GenBank acession: |
AF324219 |
| Entrez gene record: |
79058 |
| Pubmed identfication: |
11244503 10506710 |
| RefSeq identity: |
NM_024083 |
| Classification: |
UBX domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000178438 |