| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TUG/ASPC |
| Specificity: |
This antibody reacts specifically with TUG/ASPC |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TUG/ASPC |
| Gene ID: |
79058 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes, Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin, Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, Insulin mobilizes this pool of retained Glut4 by releasing the tether, TUG (ASPL in humans) regulates the trafficking of glucose via Glut4, TUG acts by trapping endocytosed Glut4 and tethering it intracellularly, fat metabolism and prolonged longevity, it is necessary for sustained growth, normal cellular glucose, Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ASPS ASPL UBXD9 UBXN9 TUG |
| Also known as: |
TUG/ASPC Polyclonal Antibody |
| Other name: |
Anti-TUG/ASPC Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TUG/ASPC |
| Short name: |
Anti-TUG/ASPC (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TUG/ASPC (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13825 |
| Gene: |
ASPSCR1 |
More about : ASPSCR1 |
| Long gene name: |
ASPSCR1, UBX domain containing tether for SLC2A4 |
| Synonyms gene name: |
alveolar soft part sarcoma chromosome region, candidate 1 |
| Synonyms name: |
UBX domain protein 9 Tether containing UBX domain for GLUT4 |
| Locus: |
17q25, 3 |
| Discovery year: |
2001-04-05 |
| GenBank acession: |
AF324219 |
| Entrez gene record: |
79058 |
| Pubmed identfication: |
11244503 10506710 |
| RefSeq identity: |
NM_024083 |
| Classification: |
UBX domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000178438 |