| Long name: |
TUG/ASPC Primary Polyclonal Antibody |
| Also known as: |
TUG/ASPC PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TUG/ASPC |
| Specificity: |
This is a highly specific antibody against TUG/ASPC |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TUG/ASPC |
| Gene ID number: |
79058 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes, Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin, Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, Insulin mobilizes this pool of retained Glut4 by releasing the tether, TUG (ASPL in humans) regulates the trafficking of glucose via Glut4, TUG acts by trapping endocytosed Glut4 and tethering it intracellularly, fat metabolism and prolonged longevity, it is necessary for sustained growth, normal cellular glucose, Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ASPC, ASPC1_HUMAN, ASPCR 1, ASPCR1, ASPL, ASPS, ASPSCR 1, Alveolar soft part sarcoma chromosome region candidate 1 human, Alveolar soft part sarcoma locus, Aspscr1, FLJ45380, RCC 17, RCC17, Renal papillary cell carcinoma protein 17, TUG, Tether containing UBX domain for GLUT4, Tether containing a UBX domain for GLUT4, UBX domain containing protein 9, UBX domain protein 9, UBX domain-containing protein 9, UBXD 9, UBXD9, UBXN 9, UBXN9, renal cell carcinoma gene on chromosome 17, renal cell carcinoma papillary 17, Alveolar soft part sarcoma chromosomal region candidate gene 1 protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TUG/ASPC |
| Short name: |
TUG/ASPC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TUG/ASPC (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13825 |
| Gene: |
ASPSCR1 |
More about : ASPSCR1 |
| Long gene name: |
ASPSCR1, UBX domain containing tether for SLC2A4 |
| Synonyms gene name: |
alveolar soft part sarcoma chromosome region, candidate 1 |
| Synonyms: |
ASPS ASPL UBXD9 UBXN9 TUG |
| Synonyms name: |
UBX domain protein 9 Tether containing UBX domain for GLUT4 |
| Locus: |
17q25, 3 |
| Discovery year: |
2001-04-05 |
| GenBank acession: |
AF324219 |
| Entrez gene record: |
79058 |
| Pubmed identfication: |
11244503 10506710 |
| RefSeq identity: |
NM_024083 |
| Classification: |
UBX domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000178438 |