| Long name: |
ALEXA FLUOR 488 Conjugated, THEMIS Polyclonal Antibody |
| Also known as: |
Anti-THEMIS PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
THEMIS |
| Specificity: |
This is a highly specific antibody against THEMIS |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
300-350/641 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human THEMIS |
| Gene ID Number: |
387357 |
| Swiss Prot: |
Q8N1K5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity), Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells, Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
bA325O24, 3 , 4 FLJ40584 bA325O24 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the THEMIS Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
THEMIS |
| Short name: |
THEMIS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, thymocyte selection associated (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
THEMIS and IDBG-632941 and ENSBTAG00000015615 and 540554, THEMIS and IDBG-96262 and ENSG00000172673 and 387357, Themis and IDBG-141613 and ENSMUSG00000049109 and 210757, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0008180 and COP9 signalosome and cellular component this GO :0043368 and positive T cell selection and biological process this GO :0043383 and negative T cell selection and biological process this GO :0050852 and T cell receptor signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, thymocyte selection associated |
| Identity: |
21569 |
| Gene: |
THEMIS |
More about : THEMIS |
| Long gene name: |
thymocyte selection associated |
| Synonyms gene: |
C6orf207 C6orf190 TSEPA |
| Synonyms gene name: |
chromosome 6 open reading frame 207 chromosome 6 open reading frame 190 thymocyte selection pathway associated |
| Synonyms name: |
thymocyte expressed molecule involved in selection |
| Locus: |
6q22, 33 |
| Discovery year: |
2003-11-25 |
| GenBank acession: |
AK094863 |
| Entrez gene record: |
387357 |
| Pubmed identfication: |
19597499 19597498 19597497 |
| RefSeq identity: |
NM_001010923 |
| Havana BLAST/BLAT: |
OTTHUMG00000015534 |