| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
THEMIS |
| Specificity: |
This antibody reacts specifically with THEMIS |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human THEMIS |
| Gene ID: |
387357 |
| Swiss Prot: |
Q8N1K5 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity), Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells, Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
bA325O24, 3 , 4 FLJ40584 bA325O24 |
| Also known as: |
THEMIS Polyclonal Antibody |
| Other name: |
Anti-THEMIS Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
THEMIS |
| Short name: |
Anti-THEMIS (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-thymocyte selection associated (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
THEMIS and IDBG-632941 and ENSBTAG00000015615 and 540554, THEMIS and IDBG-96262 and ENSG00000172673 and 387357, Themis and IDBG-141613 and ENSMUSG00000049109 and 210757, nuclei, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0008180 and COP9 signalosome and cellular component this GO :0043368 and positive T cell selection and biological process this GO :0043383 and negative T cell selection and biological process this GO :0050852 and T cell receptor signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, thymocyte selection associated |
| Identity: |
21569 |
| Gene: |
THEMIS |
More about : THEMIS |
| Long gene name: |
thymocyte selection associated |
| Synonyms gene: |
C6orf207 C6orf190 TSEPA |
| Synonyms gene name: |
chromosome 6 open reading frame 207 chromosome 6 open reading frame 190 thymocyte selection pathway associated |
| Synonyms name: |
thymocyte expressed molecule involved in selection |
| Locus: |
6q22, 33 |
| Discovery year: |
2003-11-25 |
| GenBank acession: |
AK094863 |
| Entrez gene record: |
387357 |
| Pubmed identfication: |
19597499 19597498 19597497 |
| RefSeq identity: |
NM_001010923 |
| Havana BLAST/BLAT: |
OTTHUMG00000015534 |