| Long name: |
ASIC3a/ASIC3 Primary Polyclonal Antibody |
| Also known as: |
ASIC3a/ASIC3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ASIC3a/ASIC3 |
| Specificity: |
This is a highly specific antibody against ASIC3a/ASIC3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASIC3 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Generates a biphasic current with a fast inactivating and a slow sustained phase, Heteromeric channel assembly seems to modulate channel properties, In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, May be involved in hyperalgesia, May play a role in mechanoreception, damaged or inflamed tissue, which is gated by extracellular protons and inhibited by the diuretic amiloride, Cation channel with high affinity for sodium |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ACCN 3, ACCN3, ASIC 3, ASIC3, ASIC3_HUMAN, Acid sensing ion channel 3, Acid-sensing ion channel 3, Amiloride sensitive cation channel 3, Amiloride sensitive cation channel 3 testis, Amiloride-sensitive cation channel 3, DRASIC, Modulatory subunit of ASIC 2a, Modulatory subunit of ASIC2a, Neuronal amiloride sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Proton gated cation channel subunit, SLNAC 1, SLNAC1, TNaC 1, TNaC1, Testis sodium channel 1, hASIC 3, hASIC3, hTNaC 1, hTNaC1, ASICs3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ASIC3a/ASIC3 |
| Short name: |
ASIC3a/ASIC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ASIC3a/ASIC3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
101 |
| Gene: |
ASIC3 |
More about : ASIC3 |
| Long gene name: |
acid sensing ion channel subunit 3 |
| Synonyms gene: |
ACCN3 |
| Synonyms gene name: |
amiloride-sensitive cation channel 3, testis acid-sensing (proton-gated) ion channel 3 |
| Synonyms: |
TNaC1 DRASIC |
| Synonyms name: |
testis sodium channel 1 |
| Locus: |
7q36, 1 |
| Discovery year: |
1999-05-04 |
| GenBank acession: |
AB010575 |
| Entrez gene record: |
9311 |
| Pubmed identfication: |
9571199 9744806 |
| RefSeq identity: |
NM_004769 |
| Classification: |
Acid sensing ion channel subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000158685 |