| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ACCN3 / ASIC3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Intented use: |
This ASIC3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UHC3 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing of this gene generates three transcript variants encoding distinct isoforms, In addition, The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes, The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, a heteromeric association between this member and ACCN1/ASIC2 has been observed as proton-gated channels sensitive to gadolinium, and a large extracellular loop, two hydrophobic transmembrane regions, which has many cysteine residues with conserved spacing, This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily |
| Immunogen: |
A portion of amino acids 55-83 from the human protein was used as the immunogen for this ASIC3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ASIC3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ACCN3 / ASIC3 |
| Short name: |
ACCN3 Antibody / ASIC3 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ACCN3 (Antibody to) / ASIC3 |
| Alternative technique: |
antibodies |
| Identity: |
101 |
| Gene: |
ASIC3 |
More about : ASIC3 |
| Long gene name: |
acid sensing ion channel subunit 3 |
| Synonyms gene: |
ACCN3 |
| Synonyms gene name: |
amiloride-sensitive cation channel 3, testis acid-sensing (proton-gated) ion channel 3 |
| Synonyms: |
TNaC1 DRASIC |
| Synonyms name: |
testis sodium channel 1 |
| Locus: |
7q36, 1 |
| Discovery year: |
1999-05-04 |
| GenBank acession: |
AB010575 |
| Entrez gene record: |
9311 |
| Pubmed identfication: |
9571199 9744806 |
| RefSeq identity: |
NM_004769 |
| Classification: |
Acid sensing ion channel subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000158685 |