| Long name: |
FITC Conjugated, CNG4/GARP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CNG4/GARP |
| Specificity: |
This is a highly specific antibody against CNG4/GARP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human CNG4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CNG channels are essential components of olfactory and visual transduction (1, CNG channels have been implicated in other areas (4-6), CNG1, CNG1 and CNG4, CNG1 is also expressed in medium-sized and small-sized arteries, CNG2, CNG2, CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2, CNG4, CNG4, CNG4, In olfactory neurons, In rod photoreceptors, The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1, The beta subunits consist of CNG4-6 and, but rather modify the properties of channels (1, do not form functional channels, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4), unlike the alpha subunits, which give rise to a current in response to cGMP (1-3), which open and depolarize the cell in response to cAMP (1-3), 1 and CNG4, 1 combine to form Ca ion permeable channels, 2 have been detected in the rat pineal gland (5), 2), 2), 2), 2), 3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6), 3 and CNG5 form Ca2+ permeable channels, 3), Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CNCG3L, CNCG4, CNG 4, CNG channel 4, CNG channel beta 1, CNG-4, CNG4, CNGB 1, CNGB1, CNGB1B, CNGB1_HUMAN, Cyclic nucleotide gated cation channel, Cyclic nucleotide gated cation channel 4, Cyclic nucleotide gated cation channel beta 1, Cyclic nucleotide gated cation channel gamma, Cyclic nucleotide gated cation channel modulatory subunit, Cyclic nucleotide gated channel beta 1, Cyclic nucleotide gated channel photoreceptor cGMP gated 3 gamma like, GAR1, Glutamic acid rich protein, RCNC2, RCNCb, RCNCbeta, RP45, CNCG2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CNG4/GARP Conjugated |
| Short name: |
FITC Conjugated, CNG4/GARP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CNG4/GARP (Antibody to) |
| Alternative technique: |
antibodies |