| Long name: |
ALEXA FLUOR 350 Conjugated, CNG4/GARP Polyclonal Antibody |
| Also known as: |
Anti-CNG4/GARP PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CNG4/GARP |
| Specificity: |
This is a highly specific antibody against CNG4/GARP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CNG4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CNG channels are essential components of olfactory and visual transduction (1, CNG channels have been implicated in other areas (4-6), CNG1, CNG1 and CNG4, CNG1 is also expressed in medium-sized and small-sized arteries, CNG2, CNG2, CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2, CNG4, CNG4, CNG4, In olfactory neurons, In rod photoreceptors, The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1, The beta subunits consist of CNG4-6 and, but rather modify the properties of channels (1, do not form functional channels, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4), unlike the alpha subunits, which give rise to a current in response to cGMP (1-3), which open and depolarize the cell in response to cAMP (1-3), 1 and CNG4, 1 combine to form Ca ion permeable channels, 2 have been detected in the rat pineal gland (5), 2), 2), 2), 2), 3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6), 3 and CNG5 form Ca2+ permeable channels, 3), Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
CNCG3L, CNCG4, CNG 4, CNG channel 4, CNG channel beta 1, CNG-4, CNG4, CNGB 1, CNGB1, CNGB1B, CNGB1_HUMAN, Cyclic nucleotide gated cation channel, Cyclic nucleotide gated cation channel 4, Cyclic nucleotide gated cation channel beta 1, Cyclic nucleotide gated cation channel gamma, Cyclic nucleotide gated cation channel modulatory subunit, Cyclic nucleotide gated channel beta 1, Cyclic nucleotide gated channel photoreceptor cGMP gated 3 gamma like, GAR1, Glutamic acid rich protein, RCNC2, RCNCb, RCNCbeta, RP45, CNCG2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
CNG4/GARP |
| Short name: |
CNG4/GARP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, CNG4/GARP (Antibody to) |
| Alternative technique: |
antibodies |