| Long name: |
ALEXA FLUOR 647 Conjugated, MGLUR1 + MGLUR5 Polyclonal Antibody |
| Also known as: |
Anti-MGLUR1 + MGLUR5 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MGLUR1 + MGLUR5 |
| Specificity: |
This is a highly specific antibody against MGLUR1 + MGLUR5 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission, For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores, Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase, In expression systems, Recently, The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a, The Group-II receptors in include mGluR2 and mGluR3, These receptors are called metabotropic glutamate receptors, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins, Glutamate is the main excitatory neurotransmitter in the brain |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MGLUR5 GPRC1E mGlu5 PPP1R86 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MGLUR1 + MGLUR5 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MGLUR1 + MGLUR5 |
| Short name: |
MGLUR1 + MGLUR5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, MGLUR1 and MGLUR5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4597 |
| Gene: |
GRM5 |
More about : GRM5 |
| Long gene name: |
glutamate metabotropic receptor 5 |
| Synonyms gene name: |
glutamate receptor, metabotropic 5 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 86 |
| Locus: |
11q14, 2-q14, 3 |
| Discovery year: |
1993-10-22 |
| GenBank acession: |
D28538 |
| Entrez gene record: |
2915 |
| Pubmed identfication: |
7908515 |
| RefSeq identity: |
NM_000842 |
| Classification: |
Glutamate metabotropic receptors Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000134306 |