| Catalog number: | bs-12014R-A555 |
|---|---|
| Price: | 597 € |
| Supplier: | MBS Polyclonals_1 |
| Product name: | MGLUR1 + MGLUR5 Antibody, ALEXA FLUOR 555 |
| Quantity: | 50ug |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, MGLUR1 + MGLUR5 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-MGLUR1 + MGLUR5 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | MGLUR1 + MGLUR5 |
| Specificity: | This is a highly specific antibody against MGLUR1 + MGLUR5 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission, For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores, Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase, In expression systems, Recently, The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a, The Group-II receptors in include mGluR2 and mGluR3, These receptors are called metabotropic glutamate receptors, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins, Glutamate is the main excitatory neurotransmitter in the brain |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | MGLUR5 GPRC1E mGlu5 PPP1R86 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | MGLUR1 + MGLUR5 |
| Short name: | MGLUR1 + MGLUR5 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, MGLUR1 and MGLUR5 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4597 |
| Gene: | GRM5 | More about : GRM5 |
| Long gene name: | glutamate metabotropic receptor 5 |
| Synonyms gene name: | glutamate receptor, metabotropic 5 |
| Synonyms name: | protein phosphatase 1, regulatory subunit 86 |
| Locus: | 11q14, 2-q14, 3 |
| Discovery year: | 1993-10-22 |
| GenBank acession: | D28538 |
| Entrez gene record: | 2915 |
| Pubmed identfication: | 7908515 |
| RefSeq identity: | NM_000842 |
| Classification: | Glutamate metabotropic receptors Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: | OTTHUMG00000134306 |
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