| Long name: |
Cy5 Conjugated, MGLUR1 + MGLUR5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MGLUR1 + MGLUR5 |
| Specificity: |
This is a highly specific antibody against MGLUR1 + MGLUR5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission, For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores, Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase, In expression systems, Recently, The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a, The Group-II receptors in include mGluR2 and mGluR3, These receptors are called metabotropic glutamate receptors, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins, Glutamate is the main excitatory neurotransmitter in the brain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
MGLUR5 GPRC1E mGlu5 PPP1R86 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MGLUR1 + MGLUR5 Conjugated |
| Short name: |
Conjugated, MGLUR1 + MGLUR5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, MGLUR1 and MGLUR5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4597 |
| Gene: |
GRM5 |
More about : GRM5 |
| Long gene name: |
glutamate metabotropic receptor 5 |
| Synonyms gene name: |
glutamate receptor, metabotropic 5 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 86 |
| Locus: |
11q14, 2-q14, 3 |
| Discovery year: |
1993-10-22 |
| GenBank acession: |
D28538 |
| Entrez gene record: |
2915 |
| Pubmed identfication: |
7908515 |
| RefSeq identity: |
NM_000842 |
| Classification: |
Glutamate metabotropic receptors Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000134306 |