| Long name: |
Cy5, 5 Conjugated, SLC25A12/ARALAR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SLC25A12/ARALAR |
| Specificity: |
This is a highly specific antibody against SLC25A12/ARALAR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SLC25A12/ARALAR |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ARALAR, ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle, ARALAR is implicated in conferring susceptibility to schizophrenia, ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation, In addition, It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH, Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS), the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
Aralar |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
SLC25A12/ARALAR Conjugated |
| Short name: |
Conjugated, SLC25A12/ARALAR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, SLC25A12/ARALAR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10982 |
| Gene: |
SLC25A12 |
More about : SLC25A12 |
| Long gene name: |
solute carrier family 25 member 12 |
| Synonyms gene name: |
Aralar), member 12 , member 12 solute carrier family 25 (aspartate/glutamate carrier), solute carrier family 25 (mitochondrial carrier |
| Locus: |
2q31, 1 |
| Discovery year: |
1999-01-28 |
| GenBank acession: |
Y14494 |
| Entrez gene record: |
8604 |
| Pubmed identfication: |
9722566 10702666 11566871 |
| RefSeq identity: |
NM_003705 |
| Classification: |
Solute carriers EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000134290 |