| Long name: |
ALEXA FLUOR 350 Conjugated, SLC25A12/ARALAR Polyclonal Antibody |
| Also known as: |
Anti-SLC25A12/ARALAR PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SLC25A12/ARALAR |
| Specificity: |
This is a highly specific antibody against SLC25A12/ARALAR |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC25A12/ARALAR |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ARALAR, ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle, ARALAR is implicated in conferring susceptibility to schizophrenia, ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation, In addition, It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH, Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS), the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
Aralar |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
SLC25A12/ARALAR |
| Short name: |
SLC25A12/ARALAR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, SLC25A12/ARALAR (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10982 |
| Gene: |
SLC25A12 |
More about : SLC25A12 |
| Long gene name: |
solute carrier family 25 member 12 |
| Synonyms gene name: |
Aralar), member 12 , member 12 solute carrier family 25 (aspartate/glutamate carrier), solute carrier family 25 (mitochondrial carrier |
| Locus: |
2q31, 1 |
| Discovery year: |
1999-01-28 |
| GenBank acession: |
Y14494 |
| Entrez gene record: |
8604 |
| Pubmed identfication: |
9722566 10702666 11566871 |
| RefSeq identity: |
NM_003705 |
| Classification: |
Solute carriers EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000134290 |