| Long name: |
Cy3 Conjugated, PTF1A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PTF1A |
| Specificity: |
This is a highly specific antibody against PTF1A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human PTF1A |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Localizing to the nucleus, Loss of functional PTF1 can cause pancreatic progenitors to take on the normal fates of duodenal epithelia, Mutations in the gene encoding PTF1 lead to diabetes mellitus and cerebellar hypoplasia/agenesis, PTF1 contains one basic helix-loop-helix (bHLH) domain and is believed to play an important role in mammalian pancreatic development, PTF1 interacts with RBP-Jâ, a key regulator of pancreatic islet development and insulin gene transcription in beta-cells, and, functioning as a transcription factor that regulates the specification of all three pancreatic cell types, suggesting that PTF1 also plays and important role in cerebellar neurogenesis, they cooperate in regulating the expression of PDX-1 (pancreas/duodenum homeobox protein 1), together, &hellip, ¹, PTF1 is a pancreas-specific protein that functions as a component of the trimeric pancreas transcription factor 1 (PTF1) complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
PTF1-p48 bHLHa29 |
| Properties: |
1 of the PTF1A Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PTF1A Conjugated |
| Short name: |
Conjugated, PTF1A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, PTF1A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23734 |
| Gene: |
PTF1A |
More about : PTF1A |
| Long gene name: |
1a , pancreas specific transcription factor |
| Locus: |
10p12, 2 |
| Discovery year: |
2003-12-04 |
| GenBank acession: |
BK000272 |
| Entrez gene record: |
256297 |
| Pubmed identfication: |
8703005 |
| RefSeq identity: |
NM_178161 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000017815 |