| Long name: |
ALEXA FLUOR 647 Conjugated, PTF1A Polyclonal Antibody |
| Also known as: |
Anti-PTF1A PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PTF1A |
| Specificity: |
This is a highly specific antibody against PTF1A |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PTF1A |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Localizing to the nucleus, Loss of functional PTF1 can cause pancreatic progenitors to take on the normal fates of duodenal epithelia, Mutations in the gene encoding PTF1 lead to diabetes mellitus and cerebellar hypoplasia/agenesis, PTF1 contains one basic helix-loop-helix (bHLH) domain and is believed to play an important role in mammalian pancreatic development, PTF1 interacts with RBP-Jâ, a key regulator of pancreatic islet development and insulin gene transcription in beta-cells, and, functioning as a transcription factor that regulates the specification of all three pancreatic cell types, suggesting that PTF1 also plays and important role in cerebellar neurogenesis, they cooperate in regulating the expression of PDX-1 (pancreas/duodenum homeobox protein 1), together, &hellip, ¹, PTF1 is a pancreas-specific protein that functions as a component of the trimeric pancreas transcription factor 1 (PTF1) complex |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PTF1-p48 bHLHa29 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PTF1A Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
PTF1A |
| Short name: |
PTF1A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, PTF1A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23734 |
| Gene: |
PTF1A |
More about : PTF1A |
| Long gene name: |
1a , pancreas specific transcription factor |
| Locus: |
10p12, 2 |
| Discovery year: |
2003-12-04 |
| GenBank acession: |
BK000272 |
| Entrez gene record: |
256297 |
| Pubmed identfication: |
8703005 |
| RefSeq identity: |
NM_178161 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000017815 |