| Long name: |
Cy5, 5 Conjugated, PHYHIP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PHYHIP |
| Specificity: |
This is a highly specific antibody against PHYHIP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human PHYHIP |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In transgenic mice, PAHX, PHYHIP also interacts with Dyrk1A, PHYHIP interacts with the Refsum disease gene product, Significantly, a protein that that is overexpressed in brain of Down-syndrome patients, breast and several other types of cancers, indicating that PHYHIP may play a role in the CNS deficits of Refsum disease, neurologic damage and peripheral neuropathies, overexpression of PHYHIP in heart results in tachycardia and tachyarrhythmia, small intestine and ovary, the gene encoding PHYHIP is localized to a region of the short arm of human chromosome 8 that is frequently found deleted in prostate, therefore PHYHIP may participate in some of the neurological abnormalities of Down syndrome, which is characterized by cerebellar degeneration, with weak expression in ovary, PHYHIP (Phytanoyl-CoA hydroxylase-interacting protein) is a 330 amino acid protein that is strongly expressed in brain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
KIAA0273 PAHX-AP |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
PHYHIP Conjugated |
| Short name: |
Conjugated, PHYHIP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, PHYHIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16865 |
| Gene: |
PHYHIP |
More about : PHYHIP |
| Long gene name: |
phytanoyl-CoA 2-hydroxylase interacting protein |
| Synonyms gene: |
DYRK1AP3 |
| Synonyms gene name: |
phytanoyl-CoA hydroxylase interacting protein DYRK1A interacting protein 3 |
| Locus: |
8p21, 3 |
| Discovery year: |
2001-11-16 |
| GenBank acession: |
D87463 |
| Entrez gene record: |
9796 |
| Pubmed identfication: |
9039502 10686344 |
| RefSeq identity: |
NM_014759 |
| Havana BLAST/BLAT: |
OTTHUMG00000163776 |