| Long name: |
PHYHIP Primary Polyclonal Antibody |
| Also known as: |
PHYHIP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PHYHIP |
| Specificity: |
This is a highly specific antibody against PHYHIP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PHYHIP |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In transgenic mice, PAHX, PHYHIP also interacts with Dyrk1A, PHYHIP interacts with the Refsum disease gene product, Significantly, a protein that that is overexpressed in brain of Down-syndrome patients, breast and several other types of cancers, indicating that PHYHIP may play a role in the CNS deficits of Refsum disease, neurologic damage and peripheral neuropathies, overexpression of PHYHIP in heart results in tachycardia and tachyarrhythmia, small intestine and ovary, the gene encoding PHYHIP is localized to a region of the short arm of human chromosome 8 that is frequently found deleted in prostate, therefore PHYHIP may participate in some of the neurological abnormalities of Down syndrome, which is characterized by cerebellar degeneration, with weak expression in ovary, PHYHIP (Phytanoyl-CoA hydroxylase-interacting protein) is a 330 amino acid protein that is strongly expressed in brain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DYRK1AP3, PAHX AP1, PAHXAP1, PHYIP_HUMAN, Phytanoyl CoA hydroxylase associated protein 1, Phytanoyl CoA hydroxylase interacting protein, Similar to a putative C, phytanoyl CoA 2 hydroxylase interacting protein, phytanoyl CoA alpha hydroxylase associated protein, DYRK1A interacting protein 3, elegans gene encoded in cosmid M01B2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PHYHIP |
| Short name: |
PHYHIP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PHYHIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16865 |
| Gene: |
PHYHIP |
More about : PHYHIP |
| Long gene name: |
phytanoyl-CoA 2-hydroxylase interacting protein |
| Synonyms gene: |
DYRK1AP3 |
| Synonyms gene name: |
phytanoyl-CoA hydroxylase interacting protein DYRK1A interacting protein 3 |
| Synonyms: |
KIAA0273 PAHX-AP |
| Locus: |
8p21, 3 |
| Discovery year: |
2001-11-16 |
| GenBank acession: |
D87463 |
| Entrez gene record: |
9796 |
| Pubmed identfication: |
9039502 10686344 |
| RefSeq identity: |
NM_014759 |
| Havana BLAST/BLAT: |
OTTHUMG00000163776 |